Título del artículo:

Draft genome sequence of Brucella canis strain isolated from Mexico State, Mexico

Brucella canis is a zoonotic Gram-negative coccobacillus of significant public health concern. This bacterium harbors multiple virulence factors that facilitate infection. We report the draft genome sequence of a B. canis strain isolated from an infected dog in Mexico and provide an annotation of genes associated with its virulence factors.

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Microbiology Resource Announcements

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Petrology of serpentinites associated with the Romeral Suture Zone in the Central Cordillera (Colombia)

Serpentinized ultramafic bodies in the Romeral Suture Zone (Colombia) include lithologies from the Angelópolis Ultramafite (AU), Arquía Complex (AC) and Cajamarca Complex (CC). Serpentinites show evidence of three serpentinization events; AU serpentinites and partially serpentinized peridotites recorded a first hydration event within the ocean floor characterized by transformation of olivine to lizardite. A second serpentinization event is recorded in the AU, AC and CC serpentinites, which consist in the transformation of lizardite into antigorite during prograde metamorphism. A third alteration event led to the retrogression of antigorite to chlorite and antigorite to lizardite recorded in AU and AC serpentinites (450–320°C,,350°C). Pressure–temperature pseudosections show the following peak metamorphic temperatures: (i) 325–400°C at 10 kbar for AU serpentinites, (ii) 450–480°C at 15–20 kbar for AC serpentinites and (iii) 475–625°C below 28 kbar for CC serpentinites. AU and CC protoliths correspond to oceanic mantle peridotites (840°C, FMQ −0.4 to 0.19), whereas the AC represents mantle wedge peridotites (689°C, FMQ 0.6–0.8). We proposed that serpentinites from Angelópolis Ultramafite and Arquía Complex represent mantle from an ancient oceanic lithosphere and mantle wedge fragments, which were subducted and mixed in the subduction channel below the Early Cretaceous Quebradagrande Arc in NW South America, subsequently exhumed forming the Romeral Suture Zone.

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Geological Society Special Publication

Título del artículo:

Competency Development for Employability: A Comparative Analysis by University Majors

The study analyzed the development of transversal competencies in university students from various professional programs at a Peruvian university, with an emphasis on the differences according to the academic program. Using a non-experimental comparative descriptive design, the Graduate Transversal Competencies Assessment Questionnaire (CECTGRA) was applied to a sample of 242 students distributed across six programs: Accounting, Nursing, Hospitality and Tourism, Engineering, International Business, and Psychology. The results highlight that systemic competencies are the most valued by students in terms of importance, followed by interpersonal and instrumental competencies, evidencing the relevance of critical thinking and problem-solving in professional performance. However, the Kruskal-Wallis test revealed significant differences in instrumental competencies according to the professional career (p < 0.05), with Nursing and International Business showing better results in this dimension. On the other hand, no significant differences were found in interpersonal and systemic competencies between careers, highlighting their universal importance in professional training. These findings underscore the need to adjust university curricula to strengthen instrumental competencies in specific disciplines and ensure comprehensive training that prepares students for the demands of the globalized and competitive job market.

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Proceedings of the Laccei International Multi Conference for Engineering Education and Technology

Título del artículo:

Thermochronological constraints for reconstructing the tectonic history of the northern Central Cordillera (Serranía de San Lucas), Colombia

The Northern Andes are characterized by episodes of exhumation at around 80, 60–50, 40, 25 and 15–0 Ma in the Central and Eastern Cordilleras, Santander Massif, Sierra Nevada de Santa Marta and Merída Andes. Here we present a preliminary set of low-temperature thermochronological data from the Serranía de San Lucas in the northern Central Cordillera, which demonstrate that the timing of exhumation of this region is different from that of the surrounding massifs such as the Antioquia batholith, the Santander Massif or the Sierra Nevada de Santa Marta. The thermochronological data show that the volcanic rocks of the Early Jurassic Noreán Formation exposed in the Serranía de San Lucas to the west of the Middle Magdalena River basin and the northern Santander Massif were buried beneath 6–7 km of Upper Jurassic to Upper Cretaceous/Paleocene sedimentary rocks, then slow erosional exhumation resumed at about 80–60 Ma as reflected by slow cooling rates of 2– 4°C/myr. No evidence is found for exhumation at 25 Ma as it has been previously detected in the Antioquia batholith or the Santander Massif. The Serranía de San Lucas tectonic evolution is seen in connection with Mid-Late Jurassic to Early Cretaceous extension and Late Cretaceous compression and accretion of oceanic blocks to the western margin of the South American plate, and flat slab subduction of the Caribbean plate during the Eocene–Oligocene.

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Geological Society Special Publication

Título del artículo:

Surficial serpentinite emplacements and their potential links with the mantle wedge in NW South America

Understanding the distribution and behaviour of serpentinite bodies in subduction zones is crucial for unravelling the complex processes associated with subduction dynamics. This study presents a geophysical analysis of serpentinite bodies at west of the RSZ (Romeral Suture Zone) to investigate their occurrence patterns and potential implications for the subduction system. The results indicate that serpentinite bodies in the RSZ exhibit a distinct occurrence trend. They are primarily located in zones characterized by low anomalies of geothermal gradient, negative Bouguer anomalies, positive magnetic anomalies and areas of intermediate depth seismicity (100–160 km). Notably, these bodies are predominantly distributed west of the active volcanic arc, coinciding with a region of reduced volcanism. The presence of some serpentinite bodies correlates with areas of low seismicity and high anomalies of the b-value parameter, suggesting a connection between the fracturing behaviour of these rocks and seismic activity. Detailed profiles crossing the RSZ provide further insights into the characteristics of serpentinite bodies. High anomalies of b-values are observed in areas where serpentine slivers crop out, indicating their association with ductile volumes. Seismicity patterns also support the presence of magmatic reservoirs at depths beyond 50 km, exhibiting a dominant ductile behaviour. Moreover, the absence of volcanic activity signals on the surface inside the central area of the current volcanic arc corresponds to regions of minimal seismicity, suggesting the presence of either ductile rocks or highly resistant rocks beneath the critical stress threshold. These rocks may represent magmatic bodies that are potentially connected to volcanic manifestations at the surface. Geophysical evidence, including negative anomalies, reveals lateral and depth connections between serpentinite bodies in the RSZ. These anomalies are situated within the zone of influence of the RSZ and the Western Cordillera, suggesting their association with the ongoing subduction process. The spatial distribution of serpentinite bodies is influenced by the lithospheric structure, particularly the Caldas Tear, which leads to flatter, thicker and continuous occurrences of serpentines north of the tear. Interpretations of geophysical anomalies are not conclusive in hypothesizing a possible lateral and depth connection between serpentinite bodies along the RSZ. These anomalies are also situated within a broad zone of influence between the RSZ and the Western Cordillera, suggesting their possible association with the current mantle wedge and conforming a pervasive structure in the continental lithospheric. This study proposes the presence of large serpentine layers with contrasting thicknesses at the north and south of the Caldas Tear and as extensions of the mantle wedge at the base of the continental crust. These layers may contribute to changes in plate buoyancy and provide an additional mechanism to explain the phenomenon of flat subduction. The findings highlight the importance of considering serpentinite bodies and their associated fracture regimes in understanding subduction dynamics, particularly in active subduction systems such as the RSZ. This research sheds light on the interplay between geophysical characteristics, such as b-values, a seismological parameter used to interpret seismicity rates and physical strength heterogeneity of the rocks during the earthquake cycle, and the presence of serpentinite bodies. It contributes to our understanding of subduction processes, providing valuable insights into the behaviour of rocks within the subduction system and their implications for the evolution of the RSZ. Further studies integrating geological and geophysical data will enhance our knowledge of serpentinite dynamics and their role in subduction zones, ultimately improving our comprehension of plate tectonics and associated geological hazards.

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Geological Society Special Publication

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New Coronavirus in Colombian Caribbean Bats: In Silico Analysis Reveals Possible Risk of Interspecific Jumping

Since the appearance of the Severe Acute Respiratory Syndrome (SARS) virus, there has been increased interest in understanding the role of bats in the maintenance and circulation of coronaviruses. This study aimed to describe the phylogenetic and evolutionary relationships and antigenic architecture of a new coronavirus detected in bats in the Department of Córdoba. In a surveillance study of pathogens of interest to public health, a bat Phyllostomus hastatus was captured. Rectal swabs samples were collected from the bats, and RNA was extracted and sequenced using NGS with MGI-G50 equipment. The results were analyzed using bioinformatics software. A contig of 28,619 nucleotides associated with the Coronaviridae family was obtained. Phylogenetic and molecular clock analyses of the ORF1ab gene revealed a novel divergent Alphacoronavirus that originated directly from an ancestral node. The analysis of the spike (S) protein and receptor-binding domain (RBD) is similar to that of humans (HCoV-229E) and porcine coronaviruses. In silico analysis suggests potential RBD interaction sites with human and pig cellular receptor aminopeptidase N. There is a possible risk of interspecies jumping of the new AlphaCoV/P. hastatus in humans and pigs. This is the first study to perform phylogenetic, evolutionary, and antigenic characterization of bat coronaviruses in Colombia.

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Viruses

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Scaling NeuroSymbolic AI Integration for Seismic Event Detection

This paper presents sKGlable-VEO (scalable Knowledge Graph for Volcano Event detection), a framework designed for scalable seismic event detection through the integration of NeuroSymbolic AI and Knowledge Graphs. The system is structured around three modular pipelines: 1) a Knowledge Graph construction pipeline that transforms seismic data from Seismic Analysis Code (SAC) files into an ontology-based Knowledge Graph, 2) a Deep Learning training pipeline that trains neural network models on normalized seismic signals, and 3) an event detection pipeline that classifies seismic events using the trained models. Utilizing Docker containers, the sKGlable-VEO framework enables large-scale processing of seismic data while seamlessly integrating advanced AI models. This work advances seismic event detection by merging symbolic reasoning with machine learning in a scalable, efficient pipeline.

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Lecture Notes in Computer Science

Título del artículo:

Education in endocrinology for primary care: towards comprehensive and efficient management

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Revista Medica Herediana

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Performance of Gram Stain, Leukocyte Esterase, and Nitrite in Predicting the Presence of Urinary Tract Infections: A Diagnostic Accuracy Study

Introduction: While urine culture is the gold standard for the urinary tract infection (UTI) diagnosis, delays in results highlight the need for rapid tests. This study aimed to evaluate the accuracy of urine Gram staining, leukocyte esterase, and nitrite in predicting the presence of UTI. Methods: A cross-sectional diagnostic accuracy study was conducted on adult patients undergoing urine culture at a high-complexity hospital in northeastern Colombia. The results of Gram staining and urinalysis (nitrite and leukocyte esterase) were compared to urine culture as the gold standard test, and screening performance characteristics were calculated and reported for individual and combined tests. Results: A total of 2,123 urine cultures were analyzed, with 49.8% testing positive. Escherichia coli was the most common pathogen (24.7%), and 76.17% of patients received antibiotics, primarily ceftriaxone (38.7%). Gram staining showed 56.9% (95% confidence interval (CI)=54.4 to 59.4) sensitivity and 76.8% (95% CI=72.6 to 80.5) specificity, leukocyte esterase had 67.9% (95% CI= 65.3 to 70.4) sensitivity and 84.5% (95% CI=81.4 to 87.2) specificity, and nitrite demonstrated the highest sensitivity (85.3%, 95% CI=82.0 to 88.2). The combination of Gram staining (+), leukocyte esterase (+), and nitrite (+) achieved 87.6% (95% CI=84.2 to 90.5) sensitivity and 94.6% (95% CI=93.1 to 95.9) negative predictive value (NPV), with the decision tree identifying this combination as having the highest diagnostic utility (positive likelihood ratio (PLR) = 23.77, 95% CI=18.34 to 30.80). Conclusion: It seems that, integrating urine Gram staining with leucocyte esterase and nitrite improves UTI diagnosis in high-complexity emergency settings, reducing unnecessary urine cultures and antibiotic use while enhancing resource utilization and mitigating bacterial resistance.

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Archives of Academic Emergency Medicine

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Sea surface temperature modulates El Niño and La Niña driven leptospirosis patterns: Evidence from causal machine learning in Colombia

Leptospirosis is a zoonotic disease prevalent in tropical regions influenced by climatic factors such as precipitation and soil moisture, which are regulated by the El Niño-Southern Oscillation (ENSO). This study examines the causal relationship between El Niño and La Niña episodes and leptospirosis cases in Colombia at the municipal level from 2007 to 2023. Using an ecological longitudinal design, we analyzed laboratory-confirmed cases from the National Public Health Surveillance System, environmental data from remote sensing, and socioeconomic data, employing a causal machine learning framework with doubly robust estimation and overlap weighting. We estimated the Average Treatment Effect (ATE) and the Conditional Average Treatment Effect (CATE) for three scenarios: Neutral vs. La Niña, Neutral vs. El Niño, and El Niño vs. La Niña. Results showed 10,629 cases, predominantly in males, with the highest incidence in Cali, Barranquilla, San José del Guaviare, and Cartagena. La Niña was associated with a 1.2 percentage point reduction in the probability of excess leptospirosis cases (ATE = -0.012, 95% CI: -0.015 – -0.008), while El Niño corresponded with a 7.2 percentage point increase in the probability of excess leptospirosis cases (ATE = 0.072, 95% CI: 0.041 – 0.103) compared to Neutral episodes. The El Niño vs. La Niña comparison showed no significant effect. As sea surface temperatures rose in the Pacific Ocean off the Colombian coast, the impact of both El Niño and La Niña episodes was observed to diminish, according to the CATE analysis. Regional variations, particularly in the Orinoco and Amazon regions, seem to drive these national trends, probably due to inverse hydro-climatic responses to ENSO. Refutation tests indicated the presence of remaining bias for the scenarios Neutral vs. El Niño and El Niño vs. La Niña. These findings highlight the complex interplay between climate and leptospirosis, underscoring the need for region-specific public health strategies to mitigate climate-driven disease risks in Colombia.

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Plos Global Public Health

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Validation of a simulation model in TRNSYS for an institutional photovoltaic system: Case study at the University of Santander - UDES

The objective of this study is to develop and validate an energy simulation model in TRNSYS to evaluate the performance of the grid-connected photovoltaic system installed in the Guane building of the University of Santander (UDES), located in Bucaramanga, Colombia. A technical characterization of the system was performed, followed by the design of a model in TRNSYS using real configuration, operational, and meteorological data. Subsequently, an experimental validation was carried out based on the comparison between simulated values and measured data during the year 2024, using statistical metrics such as absolute error, relative error, and accuracy. The model achieved an average relative error of 3.3%, with an average absolute difference of 146.47 W, demonstrating an overall agreement of more than 96% between simulated and experimental results. These results show that the model reproduces, with high fidelity, the behavior of the photovoltaic system under real conditions. The validated model represents a useful tool for energy management, maintenance planning, and operational optimization of institutional solar systems, and it is replicable in similar tropical contexts. In addition, it enables the exploration of expansion scenarios and sustainable energy transitions from both academic and technical perspectives.

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Periodicals of Engineering and Natural Sciences

Título del artículo:

Anomalous origin of the right coronary artery (ARCAPA): Clinical spectrum in the pediatric population based on a case report and scoping review

The anomaly of the right coronary artery originating from the pulmonary artery (ARCAPA) is an exceptionally rare congenital cardiovascular malformation, with an incidence of 0.002 % among congenital heart diseases. We present the case of a 4-month-old male infant with diaphoresis during crying, diagnosed by echocardiography and confirmed by coronary angiography. The patient underwent successful surgical reimplantation of the right coronary artery to the ascending aorta. Additionally, we conducted a scoping review of 86 pediatric cases reported in the literature, identifying clinical presentation patterns according to age groups. This report highlights the importance of timely diagnosis and early surgical management in this coronary anomaly.

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Progress in Pediatric Cardiology

Título del artículo:

Biological Mechanisms Involved in Muscle Dysfunction in COPD: An Integrative Damage–Regeneration–Remodeling Framework

Skeletal muscle dysfunction is a major systemic manifestation of COPD that shapes symptoms, exercise tolerance and mortality. Current evidence can be integrated within a Damage–Regeneration–Remodeling framework linking mechanics and biology to clinical phenotypes. Pulmonary hyperinflation and chest wall geometry chronically load the diaphragm and other respiratory muscles in COPD, whereas inactivity and exacerbation-related disuse underload locomotor muscles. Across muscle compartments, oxidative/nitrosative stress, activation of proteolytic pathways, mitochondrial and endoplasmic reticulum stress, microvascular limitations, neuromuscular junction instability, and myosteatosis degrade muscle quality. The diaphragm adapts with a fast-to-slow fiber shift, greater oxidative capacity, and sarcomere foreshortening, improving endurance, whereas limb muscles show atrophy, a glycolytic shift, reduced oxidative enzymes, extracellular matrix accrual, and fat infiltration. Translational levers that address these mechanisms include: (I) Reduce damage: bronchodilation, lung-volume reduction, oxygen, non-invasive ventilation, early mobilization, pulmonary rehabilitation, neuromuscular stimulation, and corticosteroid stewardship; (II) Enable regeneration: progressive resistance plus high-intensity/heavy-load endurance training; adequate protein and vitamin-D intake, and endocrine correction; and (III) Steer remodeling: increase physical activity (with/without coaching/telecoaching), functional assessment and CT or MRI monitoring, inspiratory-muscle training, and phenotype-guided adjuncts in selected cases. This framework clarifies why lung deflation strategies benefit inspiratory mechanics, whereas limb recovery requires behavioral and metabolic interventions layered onto systemic optimization.

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Cells

Título del artículo:

Determining factors of business failure in Latin America

Given the negative impact of business failure on job creation, socioeconomic growth, and quality of life, this article analyzes the most determining factors of this phenomenon in Latin America, based on data reported by 33,289 entrepreneurs in the Global Entrepreneurship Monitor report. Through a descriptive study with multivariate correlational statistical analysis and a multinomial logistic regression probabilistic model, the main causes of business failure in Latin America were identified as “the business does not generate profits” and “family problems.” It was concluded that variables such as “country,” “age,” and “gender” are not relevant; while “social status” and “education level” do influence the survival of companies and new businesses.

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Revista De Ciencias Sociales

Título del artículo:

Adverse childhood experiences and their impact on primary headache patients: a cross-sectional study

Introduction: Adverse Childhood Experiences (ACEs), including abuse and household dysfunction, can have lasting effects on development and health, increasing risks for chronic diseases and mental health issues. Objective: to estimate the prevalence of ACEs in this population and to determine the factors associated with these experiences. Methods: A cross-sectional study was conducted at a Colombian high-complexity institution, including adults with primary headaches according to ICHD-3 criteria. Statistical analysis involved bivariate comparisons and multivariate logistic regression, with goodness-of-fit assessed using the Hosmer and Lemeshow test. All analyses were performed using Stata 16. Results: 138 patients with primary headaches were included, 77.54% reported experiencing some form of ACEs, with 34.06% having scores of 4 or higher. Physical abuse was the most common ACE (9.13%). Women had a higher probability of reporting ACEs (OR: 8.613, 95% CI: 1.006-73.776, p = 0.049). Those with severe disability (MIDAS score) were less likely to report severe ACEs (OR: 0.293, 95% CI: 0.096-0.899, p = 0.032). Conclusion: This study demonstrates a strong relationship between adverse childhood experiences and primary headaches, highlighting the need to incorporate childhood trauma assessment into neurological practice.

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Frontiers in Psychiatry

Título del artículo:

Spatiotemporal analysis of leptospirosis in Colombia from 2007 to 2021. An environmental health metrics approach

Leptospirosis is a global zoonosis and environmental health problem because of its strong association with environmental factors. Although spatiotemporal statistics can estimate area-specific risk indicators, very few spatiotemporal analyses are done at the municipality level for extensive periods in tropical and subtropical regions, including Colombia. This study aims to assess the spatiotemporal distribution of leptospirosis in Colombia to identify significant environmental factors and produce municipality-level risk indicators. A Bayesian hierarchical model was used to estimate the association of rainfall, temperature, and overflooding with monthly leptospirosis incidence rates in all Colombian municipalities between 2007 and 2021, adjusting for sociodemographic confounders. The posterior mean was used to map the municipality-specific risk, probability of excess risk, and the municipality-specific emerging risk trend. Rainfall was associated with a higher risk of leptospirosis (rr = 1.023 [1.006–1.04]). Municipalities in the south, east, central, and west regions had the highest risk of leptospirosis, with low-risk municipalities in the central, east, north, and west regions. The overall risk decreased across the study period with only two periods of minimal variations. Multiple municipalities in the central region had a significant increasing risk. Spatiotemporal analyses provide a rich set of indicators to identify specific at-risk communities and support the development of environmental health indicators.

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Critical Public Health

Título del artículo:

Factors associated with uncontrolled hypertension in santander, colombia: baseline findings from the RE-HOPE study

In Latin America, hypertension prevalence varies widely, and control rates remain low, particularly in low-income communities, despite the proven efficacy of recommended interventions. We aimed to describe baseline characteristics and identify individual factors associated with uncontrolled hypertension in participants of the RE-HOPE study in Santander, Colombia. A cross-sectional analysis was conducted including participants ≥18 years old with hypertension, defined by self-reported history, antihypertensive use, or systolic BP ≥ 140 and/or diastolic BP ≥ 90 mmHg. Descriptive statistics were used for baseline characteristics. Mixed-effects logistic regression models stratified by sex were applied to identify factors associated with uncontrolled hypertension, adjusting for age, diabetes, obesity, medication intake, physical activity, and smoking. A total of 3 481 participants were included, with a mean age of 60.2 years (SD 13.7); 62% were female. Mean systolic and diastolic BP were 144 ± 16 mmHg and 86 ± 10 mmHg, respectively. Despite high levels of awareness (81%) and medication use (76%), only 26% of participants had controlled hypertension ( < 140/90 mmHg), and 9.6% met the target below 130/80 mmHg. Control rates were higher in the capital city compared to peripheral and rural provinces. Being female was inversely associated with uncontrolled hypertension (OR = 0.62; 95% CI: 0.52–0.75). In contrast, age ≥ 60 years (OR = 2.19; 95% CI: 1.84–2.61) and current smoking (OR = 2.48; 95% CI: 1.54–4.00) were positively associated with poor control. This study highlights significant challenges in hypertension management, particularly early diagnosis and the identification of priority groups, and emphasizes the need for targeted public health initiatives and policy actions to enhance hypertension control.

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Journal of Human Hypertension

Título del artículo:

Raman Thermometry for Thermal Characterization of Deposits Formed on Steel AISI SAE 316L in H2S–O2–N2 Atmosphere

Austenitic stainless steels are widely used in high-temperature refining operations because of their corrosion resistance and mechanical stability, which arise from thermodynamically stable surface oxides. This work analyzes the thermal properties of surface layers formed on AISI 316L under simulated N2H2SO2 atmospheres at 300–400 °C. Steel coupons are exposed for 12–36 h; morphology and composition are characterized by scanning electron microscopy/energy dispersive x-ray spectroscopy, and thermal conductivity (K) and interfacial thermal conductance (G) are quantified by noncontact micro-Raman thermometry. Spinel chromite (FeCr2O4), Cr2O3, Fe3O4, Fe2O3, and iron sulfides are identified, with stratification depending on atmosphere and exposure time. A relationship is established between O2 content and both K and G of the formed layers using noncontact micro-Raman thermometry. Compared with oxidation-only conditions, oxide/sulfidation layers exhibit systematically lower K and G, indicating improved thermal insulation and potential benefits for controlling parasitic heat transfer in refinery units handling sulfurous heavy crudes. The results link crystallinity and defect density (e.g., oxygen vacancies) with heat transport, supporting micro-Raman thermometry as a sensitive probe of thin-layer thermal behavior in complex multiphase scales.

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Steel Research International

Título del artículo:

Hybrid management of ruptured left iliac femoral contained pseudoaneurysm

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Angiologia

Título del artículo:

Height and health in Cartagena de Indias: Skeletal evidence from the 16th to the 19th century

This chapter aims to examine the variation in height within a bioarchaeological population from the colonial period excavated at the Convent of San Francisco in Cartagena de Indias (1550-1900). The study aims to explore its correlation with various skeletal stress indicators. We aim to identify possible relationships with environmental adaptation processes by comparing information. We conducted systematic and standardised macroscopic analyses on 160 individuals. The adult individuals’ stature was estimated based on the lengths of the bones in the upper and lower limbs. Additionally, the frequency and prevalence of bone lesions associated with infectious diseases and metabolic and nutritional diseases were evaluated to determine whether significant differences exist in relation to stature. The results indicate relatively tall statures for both male and female individuals, with males being taller, possibly associated with the favourable socioeconomic conditions of the population buried in the church. Additionally, it was identified that the prevalence of these lesions tends to increase with age. Considering that many of these lesions form during childhood, this suggests that individuals presenting such lesions were the most resilient to the environmental, biocultural, and nutritional stressors that caused them. Their living conditions improved once they surpassed this critical stage, enabling them to achieve greater stature during adolescence.

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Health Nutrition and Inequality in Latin America an Anthropometric History

Título del artículo:

USE OF APREMILAST FOR THE MANAGEMENT OF REFRACTORY CUTANEOUS DERMATOMYOSITIS: HOW USEFUL IS IT?

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Revista De La Facultad De Medicina Humana

Título del artículo:

Bioprospection of Biocontrol Agents for Mitigating Plant Diseases Related to Climate Change

This chapter explores bioprospecting as a key strategy for identifying biocontrol agents that can help mitigate plant diseases caused by climate change. This phenomenon, intensified by human activities, has created conditions conducive to the proliferation of phytopathogens, thereby posing a serious threat to global food security. Factors, such as increased atmospheric carbon levels, extreme temperature fluctuations, water stress, and the spread of weeds and insect vectors, further intensify this challenge. Bioprospecting is crucial for discovering microorganisms that can serve as natural biocontrol agents and play a vital role in protecting plants through mechanisms such as the production of antagonistic compounds, predation, and the induction of resistance. These microbial interactions not only control pathogens but also support plant growth and health in increasingly challenging environments. This chapter emphasizes the importance of integrating advanced omics techniques to enhance our understanding of microorganism-plant interactions, which would allow for the development of more effective and targeted bioinoculants. It also highlights the need to transfer these technologies to agricultural systems with precision and at scale, reduce reliance on chemical pesticides, and promote more sustainable farming practices. In this context, bioprospecting for phytopathogen control has emerged as a promising solution, poised to contribute to a more resilient and sustainable agricultural future in the face of climate change while also aligning with the principles of organic farming.

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Bio Control Agents for Sustainable Agriculture Diversity Mechanisms and Applications

Título del artículo:

Bio-control Agents for Sustainable Agriculture: Diversity, Mechanisms and Applications

This book covers all aspects of the diversity and core microbiome of the bio-control agents. Their bioprospecting and application at the field level is also discussed. The application of bio-control agents is unique in plant production due to various reasons, including its environment-friendly nature, management of plant resistance and incentivizing the rhizosphere to phyllosphere signaling. The chapters provide information on major plant-associated diversity of beneficial microorganisms, various pathogen management strategies, and improving plant immunity by the application of bio-control agents. Additionally, the exploitation, development, and quality control of bio-control agent-based formulations for farming systems and industrial-level production is discussed. This approach provides a novel framework for fostering sustainable development in crop production and protection. The book targets researchers, microbiology students, the biofertilizers industry, and those in agricultural and environmental fields.

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Bio Control Agents for Sustainable Agriculture Diversity Mechanisms and Applications

Título del artículo:

Correction to: Bio-control Agents for Sustainable Agriculture (Bio-control Agents for Sustainable Agriculture, 10.1007/978-981-96-3232-9)

Correction to: Chapters 11 and 20 in: D. Mitra et al. (eds.), Bio-control Agents for Sustainable Agriculture, https://doi.org/10.1007/978-981-96-3232-9 The original version of the book was inadvertently published before incorporation of the final corrections. The book has been updated with the following important changes: In Chapter 11: In Chapter 11 (p. 261 and 263), the title has been corrected as follows: Elucidating the Mechanisms of Plant Endophytes as Biocontrol Agents and Resistant Inducers Against Biotic Stress In Chapter 20 (p. 479), the name has been corrected as follows: Mudagadde G. Deeksha, Mahesh M. Jadhav, Niraj Guleria, M. N. Harish, Chaithra M, and Mritunjoy Barman

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Bio Control Agents for Sustainable Agriculture Diversity Mechanisms and Applications

Título del artículo:

Advanced electrochemical biosensing of pathogens: Harnessing the antimicrobial properties of Ib-M peptides for highly sensitive bacterial detection

This study describes the development of electrochemical biosensors with high sensitivity to detect pathogenic bacteria, including Escherichia coli O157:H7, Pseudomonas aeruginosa, and Staphylococcus aureus, in aqueous environments. The biosensors employ the antimicrobial peptides Ib-M1 and Ib-M6 as biorecognition elements, immobilized on gold nanoparticle-modified screen-printed electrodes via a self-assembled monolayer. Detection was achieved through electrochemical impedance spectroscopy, achieving remarkably low limits of detection of 1.4 CFU/mL for E. coli O157:H7 and S. aureus, and 0.8 CFU/mL for P. aeruginosa. The biosensors exhibited linear detection ranges of 0–100 CFU/mL for E. coli O157:H7 and S. aureus, and 0–75 CFU/mL for P. aeruginosa. Notably, the incorporation of carbon nanotubes significantly improved analytical sensitivity of the biosensors, particularly for E. coli O157:H7 and S. aureus. These results highlight the potential of the proposed biosensors for rapid, on-site monitoring of microbial contamination in drinking water, food processing environments, and clinical settings.

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Plos One